Monday, February 6, 2012

Formestane in treatment of breast cancer

This steroid is used in treatment of breast cancer. It is cures estrogen receptor positive breast cancer that is very common in post menopausal women. This steroid is available commercially in the market in the form of intramuscular depot injection or commonly known as Lentaron. It works by suppressing production of estrogen from anabolic steroids. It shows the tendency of androgenic activity that acts as a weak artomatase inhibitor. The action of Formestane is predominant as prohormone to 4-hydroxytesterne. It is selective in action. It is not generally taken orally as it shows weak oral bioavailability. Hence, it is taken as injections.

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